Educ Psychol Assess 20:37–46Ĭox JL, Holden JM et al (1987) Detection of postnatal depression. J Clin Endocrinol Metab 90:695–699Ĭohen J (1960) A coefficient of agreement for nominal scales. Am J Psychiatry 152(1):31–36īloch M, Rubinow DR et al (2004) Cortiosol response to oCRH in a model of pregnancy and parturition in euthymic women with and without a history of postpartum depression. APA, WashingtonĪsnis GM, McGinn LK et al (1995) Atypical depression: clinical aspects and noradrenergic function. Acta Psychiatr Scand Suppl 433:72–84ĪPA (1994) Diagnostic and statistical mannual of mental disorders (4th ed) (DSM-IV). BMJ 308:1552Īngst J, Gamma A et al (2007) Melancholia and atypical depression in the Zurich study: epidemiology, clinical characteristics, course, comorbidity and personality. The possible therapeutic consequences and the neurobiological basis for these findings warrant further research.Īltman DG, Bland JM (1994) Statistics notes: diagnostic tests 1: sensitivity and specificity. Differential diagnosis between melancholic and atypical depression in pregnancy needs to be based on pregnancy specific definitions. However some, such as mood reactivity, distinct quality of mood and sleep pattern, did discriminate. Many of the symptoms used to distinguish atypical and melancholic depression did not discriminate between these groups during pregnancy. Seventeen per cent of the cohort met SCID criteria for a depressive episode of depression at least once in pregnancy, with melancholic depression 2.4%, atypical depression 4.4% and non specified depression 10.2%. Four diagnostic groups were compared: women with melancholic, atypical or non specified depression, and those without depression. A Swiss cohort of 449 women was interviewed. A modified version of the Structured Clinical Interview for DSM IV (SCID interview) was used that allowed assessment of all DSM IV symptoms of melancholic and atypical depression with depressed and non-depressed women in pregnancy. The aim of this study was to determine whether the symptoms used for the diagnoses of atypical and melancholic depression can distinguish these subtypes during pregnancy. Atypical and melancholic subtypes of depression based on the Diagnostic and Statistical Manual (DSM) IV are important concepts, especially for biological psychiatry.
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